Lehtinen Laboratory
Address
320 Longwood Avenue Enders BuildingBoston, MA 02115
Boston, MA 02115
Summary
The Lehtinen Laboratory committed to understanding the fundamental mechanisms that regulate the development and life-long health of the mammalian brain. The brain is bathed by cerebrospinal fluid (CSF), which fills the brain's ventricles or cavities. In the developing brain, neural precursor cells divide immediately adjacent to CSF-filled ventricles. We found that the CSF proteome is both elaborate and dynamic, and that the CSF provides a rich, adaptive library of secreted factors that help coordinate neurogenesis and brain development.
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